Advanced Nanofiber Technology Inspired by Biomedical Materials

NFPatch™ uses electrospinning technology to transform collagen and active ingredients into ultra-fine dissolvable nanofibers.

The result is a completely dry, water-activated patch that eliminates the need for excess water, preservatives, and conventional serum carriers while creating intimate contact with the skin surface.

Designed in Canada by NTP Research.

Why It Works

1. The dilution problem
Conventional creams and sheet masks are 70–90% water. That means the active ingredient the thing doing the work — is a small fraction of what's applied. NFPatch encapsulates actives in a completely waterless polymer matrix, so the concentration delivered to skin is orders of magnitude higher per unit area.

2. The barrier problem
Skin's stratum corneum (the outermost layer) is specifically designed to keep things out. Most topical actives sit on the surface or penetrate only the very top layer. The nanofiber matrix dissolves on contact with skin moisture and creates a localized hydration gradient a temporary, controlled disruption of the stratum corneum that opens a pathway for actives to move through rather than around the barrier.

3. The timing problem
Conventional formats dump actives all at once. The nanofibers dissolve in a staged sequence, which means active release is spread across the wear period. This matters because:

Skin can only uptake so much at once — flooding it wastes the rest
Staged delivery keeps tissue-level concentration in the therapeutic window longer
For irritating actives (retinoids, AHAs), slower release significantly reduces surface reactivity

Science, Safety & Clinical Validation

Peer-reviewed research, laboratory testing, and pilot clinical evaluation support the potential of NFPatch™ as a next-generation nanofiber skincare platform for hydration, active delivery, and premium under-eye care.

In peer-reviewed research, a PVA/gelatin nanofiber under-eye patch containing CoQ10 demonstrated rapid hydration and active release, with 94% of CoQ10 released within 30 minutes in laboratory testing. Safety evaluations reported no skin irritation, no sensitization, and no acute systemic toxicity in preclinical testing. A pilot randomized, placebo-controlled, blinded clinical study of a CoQ10 nanofiber under-eye pad showed visible improvement in superficial under-eye wrinkles and appearance in a portion of participants, with higher satisfaction compared with placebo. These early results support NFPatch™ as a promising cosmetic nanofiber platform for hydration, active delivery, and premium under-eye skincare applications.

 Clinical and technical data available upon request for professional partners.